The fullform of dhea is Dehydroepiandrosterone which is a multi-functional steroid having the usage in biological effects in human body along iwth mammals. At present dhea is most abundant steroid found in human body taken together iwth sulfate ester. In human body dhea is produced by adrenal glands and also synthesized de novo in the brain. The dhea survives on androgen receptor in both ways such as directly and through metabolities including androstenediol and androstendione which is later goes for conversion for producing androgen testosterone, estrogens estrone and estradio. One should have information that dhea act as sigma-1 agonist which is a neurosteroid.
There are several brands available in the market such as Prastera, Prasterone, Fidelin and Fluasterone etc. One will also come across another form of dhea named as dheas and the fullform is Dehydroepiandrosterone sulfate which is a sulfate verison of it. This conversion form of dhea is used by sulfotransferase basically found in the liver,adrenals and small intestine. In certain cases dhea is seen as dheas in blood whichis 300 times higher than the free dhea in the human body. These levels of dhea shows no diurinal changes in the person. One can count the role of dhea in patients suffering from systemic lupus erythematosus. The usage of dhea is approved by U.S. Food and Drug Administration in the year 2001 and now consumers can avail it online also.
The dhea is a good news for people having heart problems as it helps in reducing cholesterol and serum lipids in the body. Dhea also used in the treatment of Alzheimer’s disease but proven to be futile. Even studies suggest that dhea supplementation in elder people shows no good signs in terms of bodycomposition , insulin sensitivity and quality of life along with physical appearance. But if someone wants to see the non-beneficial effects of dhea then it is on the memory and not only this dhea tries to recover memory in many people. It is also found that dhea plays an important role in changing subjective mood and lessening cortisol concentration which shows it prescence very highly in case of depression.